Synology RS1221+

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Status: Currently sold

A 2U, 8-bay rackmount NAS for small and medium businesses, known for its shallow chassis that fits short-depth racks or wall-mounted cabinets. The AMD Ryzen V1500B with hardware encryption and ECC memory up to 32 GB handles multiple users. M.2 SSD caching needs a separate PCIe card.

Series	x21 Series
Bays	8
CPU	AMD Ryzen V1500B
Cores / Threads	4 / 8
RAM	4 GB
CPU architecture	x86_64
Support tier	full
Warranty (years)	3
Release year	2021
RAID levels	JBOD, RAID 0, RAID 1, RAID 5, RAID 6, RAID 10, SHR
RAM (max)	32 GB
Memory slots	2
Memory generation	DDR4
Memory speed (MT/s)	2400 MT/s
ECC memory	Supported
Memory module type	SODIMM
Replaceable memory	Replaceable
Network ports	4x 1GbE
USB ports	2x USB 3.2 Gen 1
PCIe expansion	1
M.2 slots	None
Drive bay types	3.5" SATA HDD, 2.5" SATA HDD, 2.5" SATA SSD
Hot-swappable bays	Yes
CPU frequency (GHz)	2.2
Max bays with expansion unit	12
Power draw, active (W)	61.94
Power draw, hibernation (W)	29.98
Power supply (W)	350
Noise level (dBA)	53.5
Dimensions H x W x D	3.5 x 19 x 16 in (88 x 482 x 407.5 mm)
Weight	18.5 lb (8.4 kg)
Largest certified configuration observed	192 TB (8 x Synology HAT5320-24T, largest drive on the vendor HCL today; not a hardware limit)
Estimated cost to fill every bay with a certified 8 TB drive	about $2,532 new (Seagate ST8000VN004) / about $2,520 refurbished (Seagate ST8000NE001) / about $1,600 used (Synology HAT5310-8T) -- one observed eBay unit price incl. shipping x bays; quantity availability unverified
Estimated cost to fill every bay with a certified 16 TB drive	about $4,761 new (Seagate ST16000VE000) / about $5,592 refurbished (Seagate ST16000VN001) / about $3,192 used (Synology HAT5300-16T) -- one observed eBay unit price incl. shipping x bays; quantity availability unverified

View on Amazon Search eBay (used from $1589.99, new from $1929.00) Official product page + Compare

11 eBay listings checked Nov 9, 2026 · 6 new, 5 used

Documents

• Datasheet (PDF)
• Product Specifications (PDF)

Compatible Drives

150 drives certified on RS1221+'s official manufacturer compatibility list, sourced directly from Synology's own published Hardware Compatibility List. Each model links to that drive's own compatibility page.

Certified list last checked 2026-08-18.

Compatible Memory

5 memory modules listed by Synology as compatible with RS1221+. Third-party modules may also work, but are not shown here unless Synology itself lists them as compatible.

Certified list last checked 2026-09-16. Coverage varies by model. Rated module speed is not a guarantee of NAS operating speed; follow the NAS maximum capacity and installation rules.

Looking for cameras compatible with Synology NAS units? See the full Synology camera compatibility database.