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FS6420 product photo

Status: Currently sold

An enterprise 2U all-flash NAS with 24 bays for 2.5-inch SATA SSDs, built for VMs, big databases and fast file sharing. The 16-core AMD EPYC and 64 GB of ECC memory, expandable to 1 TB, give it huge headroom - it's rated for over 257,000 4K random write IOPS. This is serious data-center gear.

SeriesFS Series
Bays24
CPUAMD EPYC 7303
Cores / Threads16 / 32
RAM64 GB
CPU architecturex86_64
Support tierfull
Warranty (years)5
Release year2026
RAID levelsBasic, JBOD, RAID 0, RAID 1, RAID 5, RAID 6, RAID 10, RAID F1
PCIe slot types2x PCIe Gen 4 x16
RAM (max)1024 GB
Memory slots16
Memory generationDDR4
Memory speed (MT/s)3200 MT/s
ECC memorySupported
Memory module typeRDIMM
Replaceable memoryReplaceable
Network ports2x 10GbE
USB ports2x USB 3.2 Gen 1
PCIe expansion2 × Gen4 x16 slot (x16 link)
M.2 slotsNone
Max raw capacity1000
Drive bay types2.5" SATA SSD
Hot-swappable baysYes
CPU frequency (GHz)2.4
Power draw, active (W)164.74
Power supply (W)550
Noise level (dBA)53
Dimensions H x W x D3.5 x 19 x 28.5 in (88 x 482 x 724 mm)
Weight34.2 lb (15.5 kg)

Documents

Compatible network and expansion cards

Check the required OS, firmware, slot, bracket, and installation notes before buying.

ComponentSpecificationsEvidenceRequirements and notesBuy
Broadcom P2100GConnector: QSFP56; Host interface: PCIe 4.0 x16; Ports: 2 x 100GbEOfficially certified
Checked 2026-10-17
Firmware: 226. DSM version requirement: 7.3-81180 or later version. (Only applicable to models with DSM.)Search Amazon eBay
Marvell FastLinQ QL41134HLCUConnector: SFP+; Host interface: PCIe 3.0 x8; Ports: 4 x 10GbE; Product code: QL41134HLCUOfficially certified
Checked 2026-10-17
Firmware: 8.34.15. DSM version requirement: 6.2-24922 or later version. (Only applicable to models with DSM.)Search Amazon eBay
Synology E10G30-F2Connector: SFP+; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-10-17
DSM version requirement: 7.1.1-42962 Update 5 or later version. (Only applicable to models with DSM.); DSM Enterprise version requirement: 1.0-101178 or later version. (Only applicable to models with DSM Enterprise.); Remote Direct Memory Access (RDMA): Available on PAS7700 only. Applies to NFS over RDMA and NVMe over RDMA.Amazon eBay
Synology E10G30-T1Connector: RJ45; Host interface: PCIe 3.0 x4; Ports: 1 x 10GbEOfficially certified
Checked 2026-10-17
DSM version requirement: 7.1.1-42962 Update 5 or later version. (Only applicable to models with DSM.)Amazon eBay
Synology E10G30-T2Connector: RJ45; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-10-17
APM version requirement: 1.0-71430 or later version. (Only applicable to models with APM.); DSM version requirement: 7.1.1-42962 Update 5 or later version. (Only applicable to models with DSM.); DSM Enterprise version requirement: 1.0-101178 or later version. (Only applicable to models with DSM Enterprise.); Remote Direct Memory Access (RDMA): Available on PAS7700 only. Applies to NFS over RDMA and NVMe over RDMA.Amazon eBay
Synology E25G30-F2Connector: SFP28; Host interface: PCIe 3.0 x8; Ports: 2 x 25GbEOfficially certified
Checked 2026-10-17
APM version requirement: 1.0-71430 or later version. (Only applicable to models with APM.); DSM version requirement: 7.1.1-42962 Update 5 or later version. (Only applicable to models with DSM.); DSM Enterprise version requirement: 1.0-101178 or later version. (Only applicable to models with DSM Enterprise.); Remote Direct Memory Access (RDMA): Available on PAS7700 only. Applies to NFS over RDMA and NVMe over RDMA.; For models with an AMD Ryzen V1000 CPU, DSM version 7.2.1-69057 or above is required.Amazon eBay
Synology E10G18-T1 (EOL)Connector: RJ45; Host interface: PCIe 3.0 x4; Ports: 1 x 10GbEOfficially certified
Checked 2026-10-17
DSM version requirement: 6.2-23739-2 onward (or 6.1-15284-2 onward with DSM 6.1). (Only applicable to models with DSM.)Amazon eBay
Synology E10G18-T2 (EOL)Connector: RJ45; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-10-17
DSM version requirement: 6.2.1-23824 or later version. (Only applicable to models with DSM.)Amazon eBay
Synology E10G21-F2 (EOL)Connector: SFP+; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-10-17
DSM version requirement: 6.2.3-25426 or later version. (Only applicable to models with DSM.)Amazon eBay
Synology E25G21-F2 (EOL)Connector: SFP28; Host interface: PCIe 3.0 x8; Ports: 2 x 25GbEOfficially certified
Checked 2026-10-17
DSM version requirement: 6.2.3-25426 or later version. (Only applicable to models with DSM.); For best performance, we recommend using memory in dual-channel configuration. For instructions, refer to Hardware Installation Guide.Amazon

Compatible Drives

17 drives certified on FS6420's official manufacturer compatibility list, sourced directly from Synology's own published Hardware Compatibility List. Each model links to that drive's own compatibility page.

17certified models
1drive brands
7 TBlargest listed
17with verified extra specs
Show all 17 certified drives
17 shown
BrandModelCapacityTypeVerified drive detailsRecently observed offersStatusFirmware
SynologySAT5210-7000G details7.0 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 10000 TBWNew: $7,439.58RecommendedSCEMH5.0
SynologySAT5220-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 7000 TBWNo recent verified offerRecommendedSCEMH5.0
SynologySAT5200-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 9162 TBWNo recent verified offerRecommendedSCEMJ2.1
SynologySAT5221-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 7000 TBWNew: $3,803.00RecommendedSCEM16.3
SynologySAT5210-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 8533 TBWNo recent verified offerRecommendedSCEMH3.2
SynologySAT5210-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 4800 TBWNo recent verified offerRecommendedSCEMH3.2
SynologySAT5220-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 3500 TBWNew: $799.99RecommendedSCEMH5.0
SynologySAT5221-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 3500 TBWNew: $2,200.01 · Refurb: $2,255.63RecommendedSCEM16.3
SynologySAT5200-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 4581 TBWNo recent verified offerRecommendedSCEMJ2.1
SynologySAT5200-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 2290 TBWNo recent verified offerRecommendedSCEMJ2.1
SynologySAT5210-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 2194 TBWNo recent verified offerRecommendedSCEMH3.2
SynologySAT5221-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1700 TBWNew: $1,177.29RecommendedF3MN902
SynologySAT5220-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1700 TBWNo recent verified offerRecommendedSCEMH5.0
SynologySAT5220-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 900 TBWNo recent verified offerRecommendedSCEMH5.0
SynologySAT5210-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1097 TBWNo recent verified offerRecommendedSCEMH3.2
SynologySAT5221-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 900 TBWNo recent verified offerRecommendedF3MN902
SynologySAT5200-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1145 TBWNo recent verified offerRecommendedSCEMJ2.1

Extra drive details are published only from manufacturer-owned documents or explicit human review. Follow the model link for field-level sources.

Certified list last checked 2026-08-18.

Compatible Memory

1 memory module listed by Synology as compatible with FS6420. Third-party modules may also work, but are not shown here unless Synology itself lists them as compatible.

1certified modules
64–64 GBcapacity range
SKUCapacityDDR generationECCForm factorRated speedWarrantySource and notesBuy
D4ER02-64G64 GBDDR4ECCRDIMM-5-yearManufacturer source
Checked 2026-09-16
Search Amazon

Certified list last checked 2026-09-16. Coverage varies by model. Rated module speed is not a guarantee of NAS operating speed; follow the NAS maximum capacity and installation rules.

Looking for cameras compatible with Synology NAS units? See the full Synology camera compatibility database.