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DS1621xs+ product photo

Status: Legacy / discontinued

A 6-bay NAS with a 4-core Intel Xeon D-1527 and 8GB of ECC memory (error-correcting, up to 32GB). Two M.2 NVMe slots add SSD caching, there's a PCIe slot for upgrades, and two DX517 units take it to 16 drives. It ships with only two 1GbE ports, and it carries a 5-year warranty.

Seriesx21 Series
Bays6
CPUIntel Xeon D-1527
Cores / Threads4 / 8
RAM8 GB
CPU architecturex86_64
Support tierfull
Warranty (years)5
Release year2020
RAID levelsJBOD, RAID 0, RAID 1, RAID 5, RAID 6, RAID 10, RAID F1, SHR
PCIe slot types1x PCIe Gen 3 x8
RAM (max)32 GB
Memory slots2
Memory generationDDR4
Memory speed (MT/s)2666 MT/s
ECC memorySupported
Memory module typeSODIMM
Replaceable memoryReplaceable
Network ports1x 10GbE + 2x 1GbE
USB ports3x USB 3.2
PCIe expansion1
M.2 slots2
Max raw capacity96
Drive bay types3.5" SATA HDD, 2.5" SATA SSD
Hot-swappable baysYes
CPU frequency (GHz)2.2
Power supply (W)250
Estimated cost to fill every bay with a certified 8 TB driveabout $2,430 new (Synology HAT3310-8T) / about $1,680 refurbished (Toshiba MG06ACA800E) / about $1,200 used (Synology HAT5310-8T) -- one observed eBay unit price incl. shipping x bays; quantity availability unverified
Estimated cost to fill every bay with a certified 16 TB driveabout $3,890 new (Seagate ST16000NE000) / about $2,550 refurbished (Seagate ST16000NM001G) / about $1,854 used (Seagate ST16000NM001G) -- one observed eBay unit price incl. shipping x bays; quantity availability unverified

1 eBay listings checked Nov 9, 2026 · 1 new, 0 used (too few new listings to show a reliable new price)

Documents

Compatible network and expansion cards

Check the required OS, firmware, slot, bracket, and installation notes before buying.

ComponentSpecificationsEvidenceRequirements and notesBuy
Emulex OneConnect OCe11102-FMConnector: LC Connector; Host interface: PCIe 2.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
Tested in 10GbE standard, FCoE\iSCSI hardware acceleration is not supported.Amazon
Intel Ethernet Converged Network Adapter X520-SR2Connector: LC Connector; Host interface: PCIe 2.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
Intel Ethernet Converged Network Adapters (X520/X540) from Dell is not supported.Search Amazon eBay
Intel Ethernet Converged Network Adapter X710-DA4Connector: SFP+; Host interface: PCIe 3.0 x8; Ports: 4 x 10GbEOfficially certified
Checked 2026-09-16
Firmware: 6.01. DSM version requirement: 6.2.1-23824 or later version. (Only applicable to models with DSM.)Amazon eBay
Intel Ethernet Converged Network Adapter X710-T4Connector: RJ45; Host interface: PCIe 3.0 x8; Ports: 4 x 10GbEOfficially certified
Checked 2026-09-16
Firmware: 5.05. DSM version requirement: 6.2-23739 or later version. (Only applicable to models with DSM.)Amazon eBay
Intel Ethernet Server Adapter I350-T4Connector: RJ45; Host interface: PCIe 2.0 x4; Ports: 4 x 1GbEOfficially certified
Checked 2026-09-16
Intel Ethernet Server Adapter (I350-T4) from Dell is not supported.Amazon eBay
Intel Gigabit ET Dual Port Server AdapterConnector: RJ45; Host interface: PCIe 2.0 x4; Ports: 2 x 1GbEOfficially certified
Checked 2026-09-16
See official installation instructionsAmazon eBay
Intel Gigabit ET2 Quad Port Server AdapterConnector: RJ45; Host interface: PCIe 2.0 x4; Ports: 4 x 1GbEOfficially certified
Checked 2026-09-16
See official installation instructionsAmazon eBay
Mellanox ConnectX-3 Pro EN MCX312B-XCCTConnector: SFP+; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
Firmware: 2.33.5100. DSM version requirement: 5.2-5644 or later version. (Only applicable to models with DSM.)Amazon eBay
Mellanox ConnectX-4 Lx EN MCX4121A-XCATConnector: SFP28; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
Firmware: 14.20.1010. DSM version requirement: 6.2-23739 or later version. (Only applicable to models with DSM.); For better performance, we strongly recommend installing the network interface card into the PCIe 3.0 x8 (white) slot first. (Only applicable to RS3617xs, RS3614xs+, RS3614xs, and RS3614RPxs)Amazon eBay
Synology E10G30-F2Connector: SFP+; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
DSM version requirement: 7.1.1-42962 Update 5 or later version. (Only applicable to models with DSM.); DSM Enterprise version requirement: 1.0-101178 or later version. (Only applicable to models with DSM Enterprise.); Remote Direct Memory Access (RDMA): Available on PAS7700 only. Applies to NFS over RDMA and NVMe over RDMA.Amazon eBay
Synology E10G30-T2Connector: RJ45; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
APM version requirement: 1.0-71430 or later version. (Only applicable to models with APM.); DSM version requirement: 7.1.1-42962 Update 5 or later version. (Only applicable to models with DSM.); DSM Enterprise version requirement: 1.0-101178 or later version. (Only applicable to models with DSM Enterprise.); Remote Direct Memory Access (RDMA): Available on PAS7700 only. Applies to NFS over RDMA and NVMe over RDMA.Amazon eBay
Synology E25G30-F2Connector: SFP28; Host interface: PCIe 3.0 x8; Ports: 2 x 25GbEOfficially certified
Checked 2026-09-16
APM version requirement: 1.0-71430 or later version. (Only applicable to models with APM.); DSM version requirement: 7.1.1-42962 Update 5 or later version. (Only applicable to models with DSM.); DSM Enterprise version requirement: 1.0-101178 or later version. (Only applicable to models with DSM Enterprise.); Remote Direct Memory Access (RDMA): Available on PAS7700 only. Applies to NFS over RDMA and NVMe over RDMA.; For models with an AMD Ryzen V1000 CPU, DSM version 7.2.1-69057 or above is required.Amazon eBay
Synology E10G17-F2 (EOL)Connector: SFP+; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
DSM version requirement: 6.0.2-8451 or later version. (Only applicable to models with DSM.)Amazon eBay
Synology E10G18-T1 (EOL)Connector: RJ45; Host interface: PCIe 3.0 x4; Ports: 1 x 10GbEOfficially certified
Checked 2026-09-16
DSM version requirement: 6.2-23739-2 onward (or 6.1-15284-2 onward with DSM 6.1). (Only applicable to models with DSM.)Amazon eBay
Synology E10G18-T2 (EOL)Connector: RJ45; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
DSM version requirement: 6.2.1-23824 or later version. (Only applicable to models with DSM.)Amazon eBay
Synology E10G21-F2 (EOL)Connector: SFP+; Host interface: PCIe 3.0 x8; Ports: 2 x 10GbEOfficially certified
Checked 2026-09-16
DSM version requirement: 6.2.3-25426 or later version. (Only applicable to models with DSM.)Amazon eBay
Synology E25G21-F2 (EOL)Connector: SFP28; Host interface: PCIe 3.0 x8; Ports: 2 x 25GbEOfficially certified
Checked 2026-09-16
DSM version requirement: 6.2.3-25426 or later version. (Only applicable to models with DSM.); For best performance, we recommend using memory in dual-channel configuration. For instructions, refer to Hardware Installation Guide.Amazon

Compatible Drives

101 drives certified on DS1621xs+'s official manufacturer compatibility list, sourced directly from Synology's own published Hardware Compatibility List. Each model links to that drive's own compatibility page.

101certified models
5drive brands
24 TBlargest listed
99with verified extra specs
Show all 101 certified drives
101 shown
BrandModelCapacityTypeVerified drive detailsRecently observed offersStatusFirmware
SynologyHAT5320-24T details24.0 TB3.5" NAS HDD7200 RPM · 1024 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $1,553.83Recommended1401
SynologyHAT5310-20T details20.0 TB3.5" Enterprise HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $899.95 · Used: $1,440.13Recommended1401
SynologyHAT3320-20T details20.0 TB3.5" NAS HDD7200 RPM · 1024 MB cache · CMR · 180 TB/year workload · 1200000 h MTBF · 3-year warrantyNew: $806.19 · Used: $780.00Recommended1401
SynologyHAT5320-20T details20.0 TB3.5" NAS HDD7200 RPM · 1024 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $1,419.79Recommended1402
SynologyHAT5310-18T details18.0 TB3.5" Enterprise HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNo recent verified offerRecommended1401
SynologyHAT5300-16T details16.0 TB3.5" Enterprise HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $782.49 · Used: $399.00Recommended1402
SeagateST16000NM001G details16.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $349.00 · Refurb: $424.99RecommendedSN02
SynologyHAT5310-16T details16.0 TB3.5" Enterprise HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $1,064.99Recommended1403
SeagateST16000NE000 details16.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $648.25 · Used: $489.00RecommendedEN02
ToshibaMG08ACA16TE details16.0 TB3.5" Enterprise HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $1,199.10 · Refurb: $599.00Recommended0101
SynologyHAT3310-16T details16.0 TB3.5" NAS HDD7200 RPM · 512 MB cache · CMR · 180 TB/year workload · 1200000 h MTBF · 3-year warrantyNew: $693.99 · Used: $505.00Recommended1402
SeagateST14000NE0008 details14.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $423.65RecommendedEN01
SeagateST14000NM0018 details14.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 2500000 h MTBF · 5-year warrantyNew: $470.00RecommendedSN02
ToshibaMG07ACA14TE details14.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 3-year warrantyRefurb: $661.78 · Used: $399.00Recommended0101
Western DigitalWUH721414ALE6L4 details14.0 TB3.5" Enterprise HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyUsed: $388.00RecommendedLDGNW240
SeagateST14000NM001G details14.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $410.00 · Used: $325.00RecommendedSN02
HGSTHUH721212ALE604 details12.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNo recent verified offerRecommended-
HGSTHUH721212ALE600 details12.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $330.00 · Used: $244.99RecommendedLEGNT3D0
SeagateST12000NM0008 details12.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $450.00 · Used: $259.99RecommendedSN02
SeagateST12000NM001G details12.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $442.00 · Used: $374.99RecommendedSN02
SynologyHAT5300-12T details12.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $589.99 · Used: $379.99Recommended1401
SynologyHAT3300-12T details12.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 180 TB/year workload · 1000000 h MTBF · 3-year warrantyNo recent verified offerRecommendedPL01
SeagateST12000NE0008 details12.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $445.00 · Refurb: $384.99Recommended-
SynologyHAT3310-12T details12.0 TB3.5" NAS HDD7200 RPM · 512 MB cache · CMR · 180 TB/year workload · 1200000 h MTBF · 3-year warrantyNew: $550.99Recommended1402
Western DigitalWD121KRYZ details12.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 219 TB/year workload · 2500000 h MTBF · 5-year warrantyRefurb: $349.99Recommended-
SeagateST12000NE0007 details12.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyUsed: $397.00RecommendedEN01
Western DigitalWD121KFBX details12.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyUsed: $425.00Recommended83.00A83
ToshibaMG07ACA12TE details12.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 3-year warrantyRefurb: $501.32 · Used: $369.50Recommended-
SeagateST10000NE0008 details10.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $471.70 · Used: $257.29RecommendedEN02
SeagateST10000NM0478 details10.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 2500000 h MTBF · 5-year warrantyNew: $300.00 · Used: $444.27RecommendedSN02
SeagateST10000NE0004 details10.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $473.10Recommended-
Western DigitalWD102KFBX details10.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $500.00 · Used: $399.94Recommended83.00A83
SeagateST10000NM0086 details10.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $423.15 · Refurb: $275.00RecommendedSN05
Western DigitalWUS721010ALE6L4 details10.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $436.65 · Used: $398.98RecommendedVXGNW920
HGSTHUH721010ALE600 details10.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $321.00 · Refurb: $269.99RecommendedLHGNT384
Western DigitalWD102KRYZ details10.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyUsed: $306.19Recommended01.01H01
SeagateST10000NM001G details10.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $396.00 · Used: $299.99RecommendedSN02
Western DigitalWD101KFBX details10.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1000000 h MTBF · 5-year warrantyNew: $475.00 · Used: $349.00Recommended83.H0A03
ToshibaMG06ACA10TE details10.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 3-year warrantyNew: $500.70Recommended0104
HGSTHUH721008ALE600 details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyUsed: $248.51Recommended-
SeagateST8000NE0004 details8.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $812.33 · Used: $492.75Recommended, EOLEN02
SynologyHAT3320-8T details8.0 TB3.5" NAS HDD7200 RPM · 512 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 3-year warrantyNew: $554.00Recommended1401
SeagateST8000NE0008 details8.0 TB3.5" NAS HDD7200 RPM · CMR · 1200000 h MTBF · 5-year warrantyNo recent verified offerRecommended-
SynologyHAT3310-8T details8.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 180 TB/year workload · 1200000 h MTBF · 3-year warrantyNew: $405.00 · Used: $295.00Recommended1403
SynologyHAT5310-8T details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $1,027.37 · Used: $199.99Recommended1402
SeagateST8000NM0206 details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNo recent verified offerRecommended, EOLSN05
SynologyHAT5320-8T details8.0 TB3.5" Enterprise HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $702.17Recommended1401
SeagateST8000NM000A details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $414.99 · Used: $249.00RecommendedSN02
SynologyHAT3300-8T details8.0 TB3.5" NAS HDD5400 RPM · 256 MB cache · CMR · 180 TB/year workload · 1000000 h MTBF · 3-year warrantyUsed: $299.99RecommendedPL01
SeagateST8000NE001 details8.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $408.35 · Refurb: $314.99RecommendedEN01
Western DigitalWD8003FFBX details8.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyUsed: $295.00Recommended83.00A83
ToshibaMG06ACA800E details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $424.00 · Refurb: $279.99Recommended-
Western DigitalHUS728T8TALE6L4 details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $599.00RecommendedV8GNW460
SynologyHAT5300-8T details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $998.00 · Used: $225.00Recommended1401
Western DigitalWD8004FRYZ details8.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $399.99 · Used: $299.99Recommended01.01H01
SynologySAT5210-7000G details7.0 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 10000 TBWNew: $7,439.58RecommendedSCEMH5.0
SynologyHAT3300-6T details6.0 TB3.5" NAS HDD5400 RPM · 256 MB cache · CMR · 180 TB/year workload · 1000000 h MTBF · 3-year warrantyNew: $306.99 · Used: $211.00RecommendedPL01
SeagateST6000NE0023 details6.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $289.00 · Used: $175.00Recommended-
ToshibaMG06ACA600E details6.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2500000 h MTBF · 5-year warrantyNew: $346.54 · Refurb: $220.00Recommended-
SeagateST6000NE000 details6.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $218.32 · Used: $199.12RecommendedEN01
Western DigitalWD6003FFBX details6.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $479.06Recommended83.00A83
SeagateST6000NM021A details6.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $200.67 · Refurb: $220.00RecommendedSN02
SeagateST4000NE0025 details4.0 TB3.5" NAS HDD7200 RPM · 128 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $163.17 · Used: $129.99Recommended-
Western DigitalWD4003FFBX details4.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $289.19 · Used: $104.93Recommended-
SynologyHAT3300-4T details4.0 TB3.5" NAS HDD5400 RPM · 256 MB cache · CMR · 180 TB/year workload · 1000000 h MTBF · 3-year warrantyNew: $348.72 · Used: $175.00RecommendedPL01
SeagateST4000NE001 details4.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $139.00 · Used: $127.50RecommendedEN01
SynologyHAT5300-4T details4.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNo recent verified offerRecommended1403
SynologyHAT5320-4T details4.0 TB3.5" NAS HDD7200 RPM · 512 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $567.27Recommended1401
SeagateST4000NM002A details4.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $134.99 · Used: $79.99RecommendedSN02
ToshibaMG04ACA400E details4.0 TB3.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 550 TB/year workload · 1400000 h MTBF · 5-year warrantyNew: $270.76 · Refurb: $175.00RecommendedFP4B
SynologySAT5220-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 7000 TBWNo recent verified offerRecommendedSCEMH5.0
SynologySAT5200-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 9162 TBWNo recent verified offerRecommendedSCEMJ2.1
SynologySAT5210-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 8533 TBWNo recent verified offerRecommendedSCEMH3.1
SynologySAT5221-3840G details3.84 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 7000 TBWNew: $3,803.00RecommendedSCEM16.3
ToshibaMG04ACA300E details3.0 TB3.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 550 TB/year workload · 1400000 h MTBF · 5-year warrantyNew: $284.00 · Used: $59.99RecommendedFP4B
SeagateST2000NX0253 details2.0 TB2.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $99.99 · Refurb: $58.99RecommendedSN02
HGSTHUS722T2TALA604 details2.0 TB3.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 2000000 h MTBF · 5-year warrantyNew: $284.13 · Used: $114.99RecommendedRAGNWA07
Western DigitalWD2005FBYZ details2.0 TB3.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 219 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $87.55 · Used: $86.90Recommended-
Western DigitalWD2002FFSX details2.0 TB3.5" NAS HDD7200 RPM · 64 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $221.32 · Refurb: $411.18Recommended81.00A81
ToshibaMG04ACA200E details2.0 TB3.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 550 TB/year workload · 1400000 h MTBF · 5-year warrantyNew: $186.08 · Refurb: $300.00RecommendedFP4B
SynologyHAT3300-2T details2.0 TB3.5" NAS HDD5400 RPM · 256 MB cache · CMR · 180 TB/year workload · 1000000 h MTBF · 3-year warrantyNew: $671.92 · Used: $139.99RecommendedPL01
Western DigitalWD2005VBYZ details2.0 TB3.5" Enterprise HDD-No recent verified offerRecommended-
SeagateST2000NE001 details2.0 TB3.5" NAS HDD7200 RPM · 256 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $366.61Recommended, EOLEN01
SeagateST2000NE0025 details2.0 TB3.5" NAS HDD7200 RPM · 128 MB cache · CMR · 300 TB/year workload · 1200000 h MTBF · 5-year warrantyNew: $93.40 · Used: $317.77RecommendedEN02
SeagateST2000NM001A details2.0 TB3.5" Enterprise HDD7200 RPM · 256 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyRefurb: $270.76 · Used: $49.00RecommendedSN02
SynologySAT5210-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 4800 TBWNo recent verified offerRecommendedSCEMH3.2
SynologySAT5220-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 3500 TBWNew: $799.99RecommendedSCEMH5.0
SynologySAT5221-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 3500 TBWNew: $2,200.01 · Refurb: $2,255.63RecommendedSCEM16.3
SynologySAT5200-1920G details1.92 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 4581 TBWNo recent verified offerRecommendedSCEMJ2.1
SeagateST1000NX0313 details1.0 TB2.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $54.30 · Used: $24.99Recommended-
Western DigitalWD1005FBYZ details1.0 TB3.5" Enterprise HDD7200 RPM · 128 MB cache · 219 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $66.46 · Used: $124.99Recommended, EOL-
HGSTHUS722T1TALA604 details1.0 TB3.5" Enterprise HDD7200 RPM · 128 MB cache · CMR · 550 TB/year workload · 2000000 h MTBF · 5-year warrantyNew: $119.99 · Refurb: $200.57Recommended-
Western DigitalWD1005VBYZ details1.0 TB3.5" Enterprise HDD-No recent verified offerRecommended, EOL-
SynologySAT5200-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 2290 TBWNo recent verified offerRecommendedSCEMJ2.1
SynologySAT5210-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 2194 TBWNo recent verified offerRecommendedSCEMH3.2
SynologySAT5221-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1700 TBWNew: $1,177.29RecommendedF3MN902
SynologySAT5220-960G details0.96 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1700 TBWNo recent verified offerRecommendedSCEMH5.0
SynologySAT5210-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1097 TBWNo recent verified offerRecommendedSCEMH3.1
SynologySAT5220-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 900 TBWNo recent verified offerRecommendedSCEMH5.0
SynologySAT5221-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 900 TBWNo recent verified offerRecommendedF3MN902
SynologySAT5200-480G details0.48 TB2.5" Enterprise SSD1500000 h MTBF · 5-year warranty · 1145 TBWNo recent verified offerRecommendedSCEMJ2.1

Extra drive details are published only from manufacturer-owned documents or explicit human review. Follow the model link for field-level sources.

Certified list last checked 2026-08-18.

Compatible Memory

3 memory modules listed by Synology as compatible with DS1621xs+. Third-party modules may also work, but are not shown here unless Synology itself lists them as compatible.

3certified modules
8–16 GBcapacity range
SKUCapacityDDR generationECCForm factorRated speedWarrantySource and notesBuy
D4ECSO-2666-16G16 GBDDR4ECCSODIMM2666 MT/s5-yearManufacturer source
Checked 2026-09-16
Amazon eBay
D4ES03-16G16 GBDDR4ECCSODIMM-5-yearManufacturer source
Checked 2026-09-16
Amazon eBay
D4ES01-8G8 GBDDR4ECCSODIMM-5-yearManufacturer source
Checked 2026-09-16
Amazon eBay

Certified list last checked 2026-09-16. Coverage varies by model. Rated module speed is not a guarantee of NAS operating speed; follow the NAS maximum capacity and installation rules.

Looking for cameras compatible with Synology NAS units? See the full Synology camera compatibility database.